Myeloid-derived suppressor cells predict survival of advanced melanoma patients: comparison with regulatory T cells and NY-ESO-1- or Melan-A- specific T cells
نویسندگان
چکیده
1) Department of Dermatology, University Medical Center, Tübingen, Germany 2) German Cancer Research Center (DKFZ), Heidelberg, Germany 3) German Cancer Consortium (DKTK), Heidelberg, Germany 4) Department of Internal Medicine II, Section for Transplantation Immunology and Immunohematology, University of Tübingen, Germany 5) Department of Medical Oncology and Immunotherapy, University Hospital of Siena, Istituto Toscano Tumori, Italy 6) Department of Dermatology, University Hospital, West German Cancer Center, University Duisburg-Essen, Essen, Germany 7) Skin Cancer Research Group, School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Townsville, Australia.
منابع مشابه
Myeloid-derived suppressor cells predict survival of patients with advanced melanoma: comparison with regulatory T cells and NY-ESO-1- or melan-A-specific T cells.
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PURPOSE We initially observed that the presence of circulating NY-ESO-1- and/or Melan-A-specific T cells in patients with stage IV melanoma was significantly associated with prolonged survival. Here, we report the ways in which the phenotypes and functions of these T cells differentially affect survival in patients preselected for NY-ESO-1 and/or Melan-A reactivity. EXPERIMENTAL DESIGN We ass...
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Purpose:We initially observed that the presence of circulating NY-ESO-1– and/or Melan-A–specific T cells in patients with stage IV melanoma was significantly associated with prolonged survival. Here, we report the ways in which the phenotypes and functions of these T cells differentially affect survival in patients preselected for NY-ESO-1 and/or Melan-A reactivity. Experimental Design: We assa...
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